Latest update
2025-04-01
The data used for this project is from Yang et al., 2019: Multi-omic Profiling Reveals Dynamics of the Phased Progression of Pluripotency.
For the purpose of our project we realigned the count data for the transcriptomic data with the M11 mouse genome using STAR.
| UniprotID | GeneID | X0m | X1h | X6h | X12h | X24h | X36h | X48h | X72h | log2FC_0m_1h | log2FC_1h_6h | log2FC_6h_12h | log2FC_12h_24h | log2FC_24h_36h | log2FC_36h_48h | log2FC_48h_72h |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Q8R3W2 | 0610009B22Rik | 22.88820 | 22.58756 | 22.85770 | 22.71333 | 22.49104 | 22.28791 | 22.55330 | 22.90905 | -0.3006400 | 0.2701394 | -0.1443739 | -0.22229103 | -0.20312630 | 0.2653944 | 0.35574601 |
| Q9DCS2 | 0610011F06Rik | 25.81078 | 26.28141 | 26.05348 | 25.91008 | 25.43775 | 24.96838 | 24.84230 | 25.63992 | 0.4706273 | -0.2279365 | -0.1433905 | -0.47233934 | -0.46936564 | -0.1260783 | 0.79762014 |
| Q8BHG2 | 0610037L13Rik | 28.65140 | 28.39190 | 28.52414 | 28.30400 | 28.25237 | 28.33117 | 28.45998 | 28.38369 | -0.2595007 | 0.1322361 | -0.2201394 | -0.05162924 | 0.07879782 | 0.1288167 | -0.07629738 |
| V9GXF1 | 1110065P20Rik | 24.46039 | 25.00402 | 24.59935 | 24.25717 | 24.35595 | 24.73614 | 24.76269 | 25.85162 | 0.5436275 | -0.4046702 | -0.3421763 | 0.09878239 | 0.38018522 | 0.0265473 | 1.08893786 |
| Q8WUR0 | 1600014C10Rik | 24.30800 | 23.75634 | 24.58228 | 25.11048 | 24.86278 | 25.11902 | 24.71790 | 23.50057 | -0.5516615 | 0.8259393 | 0.5282067 | -0.24770351 | 0.25624078 | -0.4011161 | -1.21733005 |
| J3QMC0 | 1700003H04Rik | 22.82848 | 24.14460 | 23.35124 | 23.62545 | 23.32869 | 23.17345 | 23.28715 | NA | 1.3161250 | -0.7933624 | 0.2742035 | -0.29675879 | -0.15523247 | 0.1136942 | NA |
| original_id | X0h_rep1 | X0h_rep2 | X1h_rep1 | X1h_rep2 | X6h_rep1 | X6h_rep2 | X12h_rep1 | X12h_rep2 | X24h_rep1 | X24h_rep2 | X36h_rep1 | X36h_rep2 | X48h_rep1 | X48h_rep2 | X72h_rep1 | X72h_rep2 | version | ensembl_base | gene_biotype | mgi_symbol |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ENSMUSG00000121438.1 | 486 | 535 | 599 | 526 | 971 | 975 | 790 | 801 | 941 | 847 | 886 | 581 | 414 | 629 | 99 | 161 | 1 | ENSMUSG00000121438 | lncRNA | |
| ENSMUSG00000109644.3 | 41 | 32 | 60 | 44 | 62 | 45 | 101 | 84 | 112 | 110 | 98 | 97 | 31 | 36 | 41 | 41 | 3 | ENSMUSG00000109644 | lncRNA | 0610005C13Rik |
| ENSMUSG00000108652.2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | ENSMUSG00000108652 | lncRNA | 0610006L08Rik |
| ENSMUSG00000086714.3 | 12 | 23 | 14 | 21 | 21 | 21 | 19 | 26 | 20 | 26 | 33 | 23 | 30 | 61 | 50 | 71 | 3 | ENSMUSG00000086714 | lncRNA | 0610009E02Rik |
| ENSMUSG00000043644.6 | 49 | 34 | 69 | 66 | 38 | 34 | 53 | 41 | 56 | 62 | 62 | 43 | 41 | 66 | 103 | 91 | 6 | ENSMUSG00000043644 | lncRNA | 0610009L18Rik |
| ENSMUSG00000020831.19 | 33 | 27 | 34 | 55 | 48 | 41 | 65 | 63 | 57 | 81 | 70 | 65 | 47 | 60 | 83 | 73 | 19 | ENSMUSG00000020831 | protein_coding | 0610010K14Rik |
The Nono protein is a multifunctional DNA- and RNA-binding protein involved in various nuclear processes:
Nucleolin is a predominant nucleolar protein in growing eukaryotic cells, primarily associated with intranucleolar chromatin and pre-ribosomal particles. Its key functions include:
This protein is a key component of messenger ribonucleoprotein particles (mRNPs) and plays a crucial role in the regulation of germ cell mRNA stability and translation. Its functions include:
This gene encodes a subunit of the U1 snRNP (small nuclear ribonucleic particle), one of at least five snRNPs to comprise the spliceosome, which functions in processing of pre-mRNAs. The U1 snRNP has been shown to be important in defining the 5’ splice site. Alternative splicing results in multiple transcript variants
This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm.
Enables RNA binding activity. Involved in several processes, including cell cycle switching, mitotic to meiotic cell cycle; meiotic nuclear division; and spermatid differentiation. Acts upstream of or within mRNA stabilization and trophectodermal cell differentiation. Located in cytoplasm and nucleus. Is expressed in central nervous system; craniocervical region bone; dorsal root ganglion; lung; and rib. Orthologous to human RBM46
Splicing factor, which binds the consensus motif 5’-C[ACU][AU]C[ACU][AC]C-3’ within pre-mRNA and promotes specific exons inclusion during alternative splicing. Interaction with YTHDC1, a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, promotes recruitment of SRSF3 to its mRNA-binding elements adjacent to m6A sites within exons. Also functions as an adapter involved in mRNA nuclear export. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity. Involved in nuclear export of m6A-containing mRNAs via interaction with YTHDC1: interaction with YTHDC1 facilitates m6A-containing mRNA-binding to both SRSF3 and NXF1, promoting mRNA nuclear export
This protein is a member of the eIF2 complex, playing a crucial role in the early steps of protein synthesis and stress response. Key functions include:
Predicted to enable RNA binding activity and identical protein binding activity. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in brain; cortical plate; spinal cord; and trigeminal ganglion
Predicted to enable protein kinase A regulatory subunit binding activity. Predicted to be involved in epithelial structure maintenance. Predicted to be located in Golgi apparatus. Predicted to be active in cytoplasm. Is expressed in Meckel’s cartilage; chondrocranium; and olfactory epithelium.